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For tadalafil, the limited research in women suggests it may support genital arousal by increasing blood flow.70 One small 12-week study of premenopausal women with type 1 diabetes found that 5mg of tadalafil daily improved measures of genital arousal and increased clitoral blood flow.72 Another small case series reported improvement in antidepressant-associated sexual dysfunction with tadalafil.71 These studies are encouraging, but they're small and lack the rigorous evidence available for bremelanotide, so tadalafil alone wouldn't be enough to make The Mood our efficacy standout